Senior Director, Global Clinical Program Lead

As a Senior Director, Global Clinical Program Lead , you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives. The successful Study and Program Clinical Lead in Late Phase CV RM (Cardiovascular, Renal, and Metabolic diseases) will be responsible for the design, conduct, monitoring, data interpretation and reporting of clinical trials ensuring that the clinical data collected within the study will allow determination of the benefits and risks of the compound, as well as will allow for the intended label indication and price in markets globally. The individual will operate according to the highest ethical standards in compliance with internal SOPs, local regulations, laws , Good Clinical Practice , and regulatory requirements. Responsibilities Provides strategic medical and scientific knowledge (Cardiovascular, Renal, Metabolic, and/or Liver Disease ) and supports the design, initiation, execution , completion , and interpretation of a clinical study Is accountable for study designs Is accountable to deliver medical information , answers , and clarifications to Regulators, Ethic Committees, Marketing Companies, I nvestigators /S ites Often works as a Global Clinical Head (GCH) delegate across several studies ( e.g. a paediatric programme , or a set of mechanistic / differentiating studies) Can be the clinical representative on indication Global Product Teams and/or other sub-teams Has the knowledge to work across projects, with a fast learning curve when moving into new disease area Is accountable to the Global Clinical Head (GC H ) or delegate for the medical aspects and designs of studies Is responsible for driving decisions within Study Team (ST) remits together with other ST members and for solving medical issues in the study team Is accountable for the medical and ethical components of studies including patient safety on a study level in compliance with GCP Is accountable for delivery of the clinical components of all relevant study documents ( e.g Protocol, Amendments, Statistical Analysis Plan, Informed C onsent Form , Case R eport F orms, and S afety and R isk -B ased M onitoring P lans) Is accountable for ensuring that safety surveillance on a study level including the process for Adverse Events (AE)/ Serious AE reporting , the quer ying of missing/unclear data, the review of blinded safety data , and the escalat ion to the GC H /Global Safety Physician when needed. Is medically accountable for international investigator meetings, and support s Marketing Companies (MC) in national activities Approves (with the GC H ) the Clinical Study Report; including preparation and production thereof (Introduction, Results, Discussion). Is accountable for ST induction and education of new members in the study team, as well as others involved in the study Collaborates seamlessly and efficiently with global colleagues at other R&D sites May be accountable to GCH (or delegate) and l eadership for identifying risks and proposing mitigation strategies to deliver successful Phase II, III, IV or L ife C ycle M anagement studies Stays updated on relevant scientific literature Delivers analyses of clinical data in a balanced, statistically sound fashion, to drive interpretations and further idea generation Serves as a source of medical expertise for the Product Team, in analyses and interpretation of medical data Maintains a high degree of understanding and awareness on new and emerging medical development, globally. Works with international colleagues and with external Alliance partners on development initiatives and regulatory issues Applies strategic intent of AstraZeneca when working with Alliance partners, Regulatory Authorities, payers, opinion leaders, prescribers and consumers of AstraZeneca products Able to provide guidance for investigator-initiated trials in cooperation with regional marketing companies Accountable for building trustworthy relationships with steering committees/executive committees with AROs/CROs Maintains strong networks globally with KEEs, prescribers, regulators and payers Requeriments Graduate of a recognized school of medicine with an M.B.B.S., M.D. degree or equivalent, and/ or a graduate of a scientific doctora te ( e.g. PhD or PharmD) or equivalent in a scientific discipline or Pharmaceutical Medicine 3+ years clinical research expertise in relevant therapy area in study design, protocol development, monitoring and implementing clinical trials, interpreting and reporting trial results Good knowledge of biostatistics, global regulatory environment and pharmacovigilance Proven teamwork and collaboration skills Fluent in oral and written English Good presentation skills and effective communication L eadership qualities , with particular focus on collaborative working skills, trust and openness, irrespective of cultural setting AstraZeneca values and b ehaviors Agile responsiveness to scientific data Credib ility in scientific and commercial environments Desired Experience Good general medical knowledge preferably in nephrology , cardiology, metabolic, or NASH Preferably 3-5 years in the pharmaceutical industry, with an understanding of R&D, particularly of major clinical milestones and of the factors which influence d rug development An understanding of the interplay between clinical, commercial objectives , drug safety and regulatory requirements Education in Pharmaceutical Medicine Experience from different organizations AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. The annual base pay for this position ranges from 288,059.20 - 432,088.80 SD Annual . Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Date Posted 15-Jul-2026 Closing Date 28-Jul-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.