Clinical Site Liaison

Role Summary The Clinical Research Liaison (CRL) is a field‑based scientific and operational leader responsible for strengthening investigator partnerships, supporting high‑quality clinical trial execution, and driving enrollment and retention across Phase II Immunology & Inflammation (I&I) programs, with a primary focus on inflammatory bowel disease (IBD). This role blends site-facing operational leadership with medical‑scientific fluency, ensuring investigators and site teams understand both the scientific rationale and the operational expectations behind complex I&I protocols. CRLs serve as a critical bridge between Clinical Operations, Clinical Development, and Medical Affairs, bringing regional insights, scientific clarity, and proactive problem-solving to accelerate enrollment and optimize study performance.   Key Responsibilities Site Engagement & Clinical Trial Execution  Build and maintain strong relationships with PIs, sub‑Is, coordinators, and research staff across gastroenterology centers and academic institutions. Serve as the primary sponsor-facing contact for assigned sites, providing both scientific and operational support. Develop and execute site‑specific enrollment action plans tailored to local patient flow, site capabilities, and competing trials. Monitor enrollment metrics in real time and proactively intervene when sites fall behind, escalating barriers and partnering cross-functionally to remove them. Identify and resolve site challenges efficiently, delivering a high level of service. Support site initiation, activation, and ongoing conduct through clear communication, scientific alignment, and operational readiness. Respond promptly to scientific and operational inquiries outside CRA scope, escalating appropriately. Ensure consistent trial execution across sites through tailored engagement strategies developed in partnership with Clinical Operations and CRO teams. Scientific Engagement  Deliver credible, compliant scientific discussions with investigators and site staff focused on  I&I pathophysiology ,  immune pathways ,  mechanism of action , and  endpoint rationale . Provide medical-scientific clarity to reduce protocol deviations and improve data quality. Support Medical Affairs in disseminating emerging clinical data and ensuring scientific consistency across site interactions. Identify emerging scientific trends, competitive developments, and unmet needs in I&I that may influence development strategy. Insight Generation  Capture scientific, operational, and competitive insights from sites, including enrollment barriers, investigator sentiment, protocol comprehension challenges, and competitive trial activity. Communicate insights to Clinical Development, Clinical Operations, and Medical Affairs to inform study design, evidence generation priorities, and ongoing trial strategy. Support development of site-facing materials (training decks, scientific briefs, FAQs, visit flow tools). Participate in investigator meetings, advisory boards, and scientific exchange activities. Qualifications Bachelor’s degree required; advanced scientific or clinical degree strongly preferred (PharmD, PhD, MD, NP/PA, RN). 8–12+ years of experience in clinical research, clinical operations, or medical affairs. 3–5+ years in a site-facing role (CRA, MSL, CTM, Clinical Educator). Strong expertise in Immunology & Inflammation, with direct experience in autoimmune, inflammatory, or immune-mediated diseases; IBD experience strongly preferred. Demonstrated experience supporting Phase II or Phase III clinical trials. Proven ability to engage investigators, lead scientific discussions, and represent Medical Affairs in cross-functional settings. Exceptional communication skills with the ability to translate complex science into clear, compelling narratives. Comfortable operating in a fast-paced, high-growth biotech environment. Ability to travel ~60%. Seeking candidates in Boston or San Diego however location of role flexible based on level of experience.